dcanr - Differential co-expression/association network analysis
This package implements methods and an evaluation framework to infer differential co-expression/association networks. Various methods are implemented and can be evaluated using simulated datasets. Inference of differential co-expression networks can allow identification of networks that are altered between two conditions (e.g., health and disease).
Last updated 27 days ago
networkinferencegraphandnetworkdifferentialexpressionnetwork
6.75 score 6 stars 1 packages 26 scripts 269 downloadsvissE - Visualising Set Enrichment Analysis Results
This package enables the interpretation and analysis of results from a gene set enrichment analysis using network-based and text-mining approaches. Most enrichment analyses result in large lists of significant gene sets that are difficult to interpret. Tools in this package help build a similarity-based network of significant gene sets from a gene set enrichment analysis that can then be investigated for their biological function using text-mining approaches.
Last updated 27 days ago
softwaregeneexpressiongenesetenrichmentnetworkenrichmentnetworkbioinformatics
6.02 score 13 stars 18 scripts 218 downloadsSpaNorm - Spatially-aware normalisation for spatial transcriptomics data
This package implements the spatially aware library size normalisation algorithm, SpaNorm. SpaNorm normalises out library size effects while retaining biology through the modelling of smooth functions for each effect. Normalisation is performed in a gene- and cell-/spot- specific manner, yielding library size adjusted data.
Last updated 27 days ago
softwaregeneexpressiontranscriptomicsspatialcellbiology
5.77 score 9 stars 2 scripts